21 Ara 2024 Cumartesi
In vitro assessment of genotoxic and oxidative effects potentials of edible bamboo worms and weaver ants
Abstract :In the
present study we have assessed the genotoxic and oxidative effects of water
soluble extracts of Bamboo Worms, Omphisa fuscidentalis (Lepidoptera:
Pyralidae), and Weaver Ants, Oecophylla smaragdina (Hymenoptera:
Formicidae), on cultured human blood cells. The extracts were added to the
cultures at 12 different concentrations (0-2000 ppm). Micronucleus (MN) test
was used to monitor the DNA and chromosomal damage produced by aqueous extracts
in vitro. In addition, to assess the
oxidative effects, total antioxidant capacity (TAC) and total oxidant status
(TOS) levels were also measured. Our results indicated that these extracts did
not show genotoxic effects at the tested concentrations. However, the extracts
caused dose dependent alterations in both TAC and TOS levels. Based on the
findings, it was concluded that the studied insects can be consumed safely, but
it is necessary to consider the cellular damages which are likely to appear
depending on oxidative stress at higher concentrations. It has been also
suggested that this in vitro approach
for oxidative and genotoxicity assessments may be useful to evaluate the
potential health risks of edible insects.
Edible
insects, genotoxicity, oxidative status